The tissue obtained from transurethral prostatectomies was evaluated histologically and correlated to the clinical findings in 85 patients with benign prostatic hyperplasia. Hematoxylin and eosinstained tissue slides of each patients were xamined
from
10 to 25 chips. The patients were divided into 3 groups according to the following histology : predominantly glandular type (26 patients), predominantly stromal type (24 patients) and mixed type which has equal proportions of glandular and
stromal
hyperplasia (35 patients). There was no significant difference among the groups in patients age, prostatic size, weight of resected tissue and also no difference was noted in total symptom scores, irritative symptom scores and obstructive symptom
scores
at preoperative, postoperative and follow-up examination. Preoperatively there was significant difference among the three histologic groups in maximum flow at uroflowmetry, the glandular type had a mean maximum flow of 3.8ml. per second compared
to
4.8ml. per second in the stromal type and 2.3ml. per second in the mixed type (p<0.05). But there was no difference at postoperative and follow up period.
Acute retention was noted in mixed type predominantly (62.9%). In acute retention patients, preoperatively there was no difference among the groups in total symptom scores and irritative symptom scores, but postoperatively there was significant
difference among the groups (p<0.05). Notwithstanding the difference of postoperative time, the differences of total symptom scores and irriative symptom scores among the groups were lost at follow up period.
Conclusively, there was no significant difference in symptom scores among the three histologic groups but prevalence of acute retention was high in mixed group. The effect of transurethral resection of prostate according to the histologic type of
benign
prostatic hyperplasia seemed to be worse I glandular type postoperatively, but there was no significant difference among them at follow-up period.
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